GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | trans | rs2084385 | 1 | rs2084386 | chr3:196554020 | LOC646214 | chr15:21932514-21940739:- | -0.7 | -7.13 | 5.0E-12 | Total ventricular volume (Alzheimer's disease interaction) |
| BLCA | trans | rs1003719 | 1 | rs2154536 | chr21:38492147 | LZTFL1 | chr3:45865446-45957534:- | 0.31 | 6.13 | 2.19E-9 | Eye color traits |
| BLCA | trans | rs6600671 | 1 | rs2185281 | chr1:121179991 | NBPF14 | chr1:148003643-148346791:- | 0.28 | 6.19 | 1.51E-9 | Hip geometry |
| BLCA | trans | rs1056667 | 1 | rs2208331 | chr6:26507319 | ZNF322B | chr9:99957633-99961910:- | 0.45 | 7.92 | 2.6E-14 | Educational attainment |
| BLCA | trans | rs1056667 | 1 | rs2224380 | chr6:26553943 | ZNF322B | chr9:99957633-99961910:- | 0.47 | 8.29 | 1.88E-15 | Educational attainment |
| BLCA | trans | rs1056667 | 1 | rs2255070 | chr6:26501777 | ZNF322B | chr9:99957633-99961910:- | 0.46 | 8.07 | 9.21E-15 | Educational attainment |
| BLCA | trans | rs877636 | 1 | rs2292239 | chr12:56482180 | RPS26P11 | chrX:71264259-71264809:+ | 0.39 | 6.51 | 2.43E-10 | Cognitive function |
| BLCA | trans | rs1056667 | 1 | rs2393670 | chr6:26535541 | ZNF322B | chr9:99957633-99961910:- | 0.46 | 8.01 | 1.42E-14 | Educational attainment |
| BLCA | trans | rs1003719 | 1 | rs2835607 | chr21:38491973 | LZTFL1 | chr3:45865446-45957534:- | 0.31 | 6.08 | 2.86E-9 | Eye color traits |
| BLCA | trans | rs1003719 | 1 | rs2835608 | chr21:38493455 | LZTFL1 | chr3:45865446-45957534:- | 0.31 | 6.13 | 2.19E-9 | Eye color traits |
| BLCA | trans | rs1056667 | 1 | rs28558133 | chr6:26531433 | ZNF322B | chr9:99957633-99961910:- | 0.45 | 7.95 | 2.07E-14 | Educational attainment |
| BLCA | trans | rs1056667 | 1 | rs3736781 | chr6:26505362 | ZNF322B | chr9:99957633-99961910:- | 0.45 | 7.92 | 2.6E-14 | Educational attainment |
| BLCA | trans | rs1056667 | 1 | rs3736782 | chr6:26505403 | ZNF322B | chr9:99957633-99961910:- | 0.45 | 7.92 | 2.6E-14 | Educational attainment |
| BLCA | trans | rs10514688 | 1 | rs41321847 | chr3:34927004 | RXFP2 | chr13:32313679-32377008:+ | -0.43 | -6.89 | 2.27E-11 | Tonometry |
| BLCA | trans | rs4272382 | 1 | rs4272382 | chr8:8433488 | CHMP7 | chr8:23101150-23119512:+ | -0.57 | -6.02 | 4.05E-9 | Response to cytidine analogues (gemcitabine) |